Search on: SUCCINATE-COA LIGASES 
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Descriptor English:   Succinate-CoA Ligases 
Descriptor Spanish:   Succinato-CoA Ligasas 
Descriptor Portuguese:   Succinato-CoA Ligases 
Synonyms English:   CoA Synthetases, Succinyl
Ligases, Succinate-CoA
Succinate CoA Ligases
Synthetases, Succinyl CoA
Thiokinases, Succinic
Succinic Thiokinases
Succinyl CoA Synthetases
Succinyl Coenzyme A Synthetases
Succinate-CoA Ligase (GDP-Forming)
Succinate-CoA Ligases (ADP-Forming)  
Tree Number:   D08.811.464.267.500.600
Definition English:   Enzymes that catalyze the first step leading to the oxidation of succinic acid by the reversible formation of succinyl-CoA from succinate and CoA with the concomitant cleavage of ATP to ADP (EC 6.2.1.5) or GTP to GDP (EC 6.2.1.4) and orthophosphate. Itaconate can act instead of succinate and ITP instead of GTP.EC 6.2.1.-. 
History Note English:   98(76) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   13775 
Unique Identifier:   D013389 

Occurrence in VHL: 		 

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